• 文章类型: Editorial
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  • 文章类型: Journal Article
    目的研究千伏独立能力(以下,kV无关)和锡滤波器光谱整形,以与标准120kVCT协议相比,准确量化冠状动脉钙积分(CACS)和辐射剂量减少。材料和方法本前瞻性,盲人读者研究包括201名参与者(平均年龄,60岁±9.8[SD];119名女性,82名男性),从2020年10月至2021年7月接受了标准120kVCT和额外的kV无关和锡过滤器研究CT扫描。使用用于标准扫描的Qr36f内核和用于模拟人工120kV图像的研究扫描的Sa36f内核重建扫描。CACS,风险分类,和辐射剂量通过方差分析分析进行比较,Kruskal-Wallis测试,曼-惠特尼测试,Bland-Altman分析,皮尔逊相关性,和κ分析的一致性。结果没有证据表明标准120kV之间的CACS存在差异,kV独立,和锡过滤器扫描,CACS中值为1(IQR,0-48),0.6(IQR,0-58),和0(IQR,0-51),分别(P=.85)。与标准的120kV扫描相比,kV无关扫描和锡滤波扫描在CACS值中显示出极好的相关性(分别为r=0.993和r=0.999),在CACS风险分类中具有很高的一致性(分别为κ=0.95和κ=0.93)。标准120kV扫描的平均辐射剂量为2.09mSv±0.84,而与kV无关的和锡过滤器扫描将其降低至1.21mSv±0.85和0.26mSv±0.11,削减剂量为42%和87%,分别(P<.001)。结论与标准120kV扫描相比,独立于kV和锡滤波器研究的CT采集技术在CACS估计中显示出极好的一致性和较高的准确性,辐射剂量大幅减少。关键词:CT,心脏,冠状动脉,辐射安全,冠状动脉钙积分,辐射剂量减少,低剂量CT扫描,锡过滤器,kV独立补充材料可用于本文。©RSNA,2024.
    Purpose To investigate the ability of kilovolt-independent (hereafter, kV-independent) and tin filter spectral shaping to accurately quantify the coronary artery calcium score (CACS) and radiation dose reductions compared with the standard 120-kV CT protocol. Materials and Methods This prospective, blinded reader study included 201 participants (mean age, 60 years ± 9.8 [SD]; 119 female, 82 male) who underwent standard 120-kV CT and additional kV-independent and tin filter research CT scans from October 2020 to July 2021. Scans were reconstructed using a Qr36f kernel for standard scans and an Sa36f kernel for research scans simulating artificial 120-kV images. CACS, risk categorization, and radiation doses were compared by analyzing data with analysis of variance, Kruskal-Wallis test, Mann-Whitney test, Bland-Altman analysis, Pearson correlations, and κ analysis for agreement. Results There was no evidence of differences in CACS across standard 120-kV, kV-independent, and tin filter scans, with median CACS values of 1 (IQR, 0-48), 0.6 (IQR, 0-58), and 0 (IQR, 0-51), respectively (P = .85). Compared with standard 120-kV scans, kV-independent and tin filter scans showed excellent correlation in CACS values (r = 0.993 and r = 0.999, respectively), with high agreement in CACS risk categorization (κ = 0.95 and κ = 0.93, respectively). Standard 120-kV scans had a mean radiation dose of 2.09 mSv ± 0.84, while kV-independent and tin filter scans reduced it to 1.21 mSv ± 0.85 and 0.26 mSv ± 0.11, cutting doses by 42% and 87%, respectively (P < .001). Conclusion The kV-independent and tin filter research CT acquisition techniques showed excellent agreement and high accuracy in CACS estimation compared with standard 120-kV scans, with large reductions in radiation dose. Keywords: CT, Cardiac, Coronary Arteries, Radiation Safety, Coronary Artery Calcium Score, Radiation Dose Reduction, Low-Dose CT Scan, Tin Filter, kV-Independent Supplemental material is available for this article. © RSNA, 2024.
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  • 文章类型: Editorial
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  • 文章类型: Case Reports
    背景:在皮肤/性手术或创伤期间,异物在体内的保留是经常需要手术切除异物的事故和急诊科就诊的原因之一。然而,在某些情况下,这种异物的发现是在多年后发生的,从神经社会学的角度来看,患者略有受损。
    方法:一名76岁男性因阴囊体积增加而接受门诊泌尿外科检查。在超声波检查中,检测到来自固体物体的声学干扰,为此需要计算机断层扫描。计算机断层扫描显示会阴中存在细长的金属体。然后安排在手术室中去除异物。识别出位于脓肿异物肉芽肿内的10厘米长的不锈钢钉,并通过阴囊通道去除。四天后,由于皮瓣的最小坏死,进行了新的手术厕所。然后在接下来的一周中,患者在手术室中进行了另外三种敷料。通过次要意图进行愈合,直到获得手术伤口的完美愈合。
    结论:在感染的情况下从会阴去除异物可能具有挑战性。仔细的注意和术后的敷料对于病例的成功至关重要。
    BACKGROUND: The retention of foreign bodies inside the body during ludic/sexual procedures or for traumatism represents one of the causes of visits to accident and emergency departments that often requires surgical removal of the foreign body. However, there are cases where the discovery of such foreign bodies takes place after many years, as in patients that are slightly compromised from a neuro-sociological point of view.
    METHODS: A 76-year-old male presented to an outpatient urological examination due to an increase in scrotal volume. At the ultrasound check, an acoustic interference from a solid object was detected, for which computed tomography was requested. The computed tomography scan revealed the presence of an elongated metal body in the perineum. The removal of the foreign body in the operating theatre was then scheduled. A 10 cm long stainless-steel nail located within an abscessed foreign body granuloma was identified and removed via a scrotal access. Four days later, a new surgical toilet was performed due to minimal necrosis of the skin flaps. The patient then performed three more dressings in the operating theatre during the following week. Healing took place by secondary intention until a perfect healing of the surgical wound was obtained.
    CONCLUSIONS: Removal of foreign bodies from the perineum in case of infection can be challenging. Careful attention and postoperative dressings are crucial for the success of the case.
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  • 文章类型: Journal Article
    目的:评估结合超声(US)的B模式和彩色多普勒功能的诊断效能,以建立可靠的独立诊断工具来诊断输尿管结石,作为非对比增强计算机断层扫描(NCCT)的替代方法。
    方法:共纳入140例使用NCCT诊断为输尿管结石的连续患者。在同一天,B模式和彩色多普勒超声均由经验丰富的放射科医生进行,他对NCCT扫描结果一无所知。记录US对结石检测的诊断率。此外,我们分析了基线患者和结石特征与使用US进行结石检测的准确性之间的关联.
    结果:US表现出91.43%的高灵敏度,检测到140个石头病灶中的128个。值得注意的是,与骨盆区域相比,近端和输尿管膀胱交界处(UVJ)段的输尿管结石很容易识别(p=0.0003)。此外,肾积水增强了美国检测结石的能力(p<0.0001)。相反,腹部气体和肥胖对美国的能力产生不利影响(分别为p<0.0001和p=0.009)。石头的一面,尺寸,和密度无统计学意义(p>0.05)。
    结论:US具有彩色多普勒功能,可以作为输尿管结石患者诊断工作的可靠和安全的替代成像方式。包括石头位置在内的因素,肾积水,重量和腹部气体显著影响其准确性。
    OBJECTIVE: To assess the diagnostic efficacy of integrating B-mode and color Doppler capabilities of ultrasound (US) to establish a robust standalone diagnostic tool for the diagnosis of ureteric stones as an alternative to non-contrast-enhanced computed tomography (NCCT).
    METHODS: A total of 140 consecutive patients diagnosed with ureteric stones using NCCT were enrolled. On the same day, US in both B-mode and Color Doppler was performed by an experienced radiologist who was blinded to the NCCT scan results. The diagnostic rate of US for stone detection was recorded. Additionally, baseline patient and stone characteristics were analyzed for their association with the accuracy of stone detection using US.
    RESULTS: US exhibited a high sensitivity of 91.43%, detecting 128 out of 140 stone foci. Notably, ureteric stones in the proximal and uretero-vesical junction (UVJ) segments were readily identifiable compared to those in the pelvic region (p = 0.0003). Additionally, hydronephrosis enhanced the US\'s ability to detect stones (p < 0.0001). Conversely, abdominal gases and obesity adversely affected US capabilities (p < 0.0001 and p = 0.009, respectively). Stone side, size, and density showed no statistically significant impact (p > 0.05).
    CONCLUSIONS: US with its color Doppler capabilities could serve as a reliable and safe alternative imaging modality in the diagnostic work up of patients with ureterolithiasis. Factors including stone location, Hydronephrosis, weight and abdominal gases significantly influenced its accuracy.
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  • 文章类型: Journal Article
    SAPIEN3(S3)是一种普遍存在的经导管重做主动脉瓣(TAV)置换,用于退化的Evolut瓣膜,但S3-in-Evolut的S3大小仍不清楚。我们试图将体内计算机断层扫描(CT)尺寸对S3-in-Evolut的redo-TAV可行性的影响与传统的台式尺寸进行比较。
    分析了2015年7月至2021年12月期间使用EvolutR/PRO/PRO+治疗的290例患者的CT扫描。在节点6、-5和-4处使用S3流出/新裙平面(NSP)模拟S3-in-Evolut。通过平均NSP水平的Evolut支架框架的4个区域和下面的3个节点来确定S3的CT尺寸。如果NSP低于冠状动脉,redo-TAV被认为是可行的,或最窄的瓣膜(虚拟S3)到主动脉的距离>4mm。使用预测的索引有效孔口面积估计假体-患者不匹配的风险。
    与台式尺寸相比,CT大小的S3大小较小,在6节点为82%,在5节点为81%,在4节点为84%。与CT大小小于台式大小相关的因素是较大的指数Evolut大小,指数Evolut的膨胀不足,植入深度较浅(均P<0.05)。CT大小在节点6处增加了重做TAV的可行性8%,在节点5处增加了10%,在节点4处增加了4%。Redo-TAV的可行性随着环尺寸的增加而增加,窦管连接尺寸,冠状动脉高度,索引Evolut大小,更深的Evolut植入深度,NSP水平较低(均P<0.05)。CT大小估计的严重假体-患者不匹配的风险略高(6节点为9%,5节点为7%,4节点为6%)。这可以通过改变NSP来缓解。
    与台式尺寸相比,S3-in-Evolut的CT尺寸与重做TAV的更高可行性相关,潜在地降低过度尺寸和S3膨胀不足的风险。使用真实世界的临床数据进一步验证是必要的。
    UNASSIGNED: SAPIEN3 (S3) is a ubiquitous redo-transcatheter aortic valve (TAV) replacement alternative for degenerated Evolut valves, but S3 sizing for S3-in-Evolut remains unclear. We sought to compare the impact of in vivo computed tomography (CT)-sizing on redo-TAV feasibility for S3-in-Evolut with traditional bench-sizing.
    UNASSIGNED: CT scans of 290 patients treated using Evolut R/PRO/PRO+ between July 2015 and December 2021 were analyzed. S3-in-Evolut was simulated using S3 outflow/neoskirt plane (NSP) at node-6, -5, and -4. CT-sizing for S3 was determined by averaging 4 areas of the Evolut stent frame at NSP level and 3 nodes below. Redo-TAV was deemed feasible if the NSP was below the coronaries, or the narrowest valve (virtual S3)-to-aorta distance was >4 mm. Risk of prosthesis-patient mismatch was estimated using predicted indexed-effective orifice area.
    UNASSIGNED: Compared with bench-sizing, CT-sizing yielded smaller S3 size in 82% at node-6, 81% at node-5, and 84% at node-4. Factors associated with CT-sizing less than bench-sizing were larger index Evolut size, underexpansion of index Evolut, and shallower implant depth (all P<0.05). CT-sizing increased redo-TAV feasibility by +8% at node-6, +10% at node-5, and +4% at node-4. Redo-TAV feasibility increased with annulus size, sinotubular junction dimensions, coronary heights, index Evolut size, deeper Evolut implant depth, and lower NSP levels (all P<0.05). CT-sizing had a slightly higher estimated risk of severe prosthesis-patient mismatch (9% at node-6, 7% at node-5, and 6% at node-4), which could be mitigated by changing the NSP.
    UNASSIGNED: CT-sizing for S3-in-Evolut is associated with higher feasibility of redo-TAV compared with bench-sizing, potentially reducing the risk of excessive oversizing and S3 underexpansion. Further validation using real-world clinical data is necessary.
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  • 文章类型: Case Reports
    我们报告了一例通过腹外缝合进行初次闭合修复的Morgagni疝。此外,我们回顾了腹腔镜修复的Morgagni疝病例,已知疝气缺损的大小,建立网格利用率的尺寸标准。一名87岁的妇女因右上腹部疼痛和呕吐来到我们医院。她没有腹部手术或外伤史。胸部X线摄影和计算机断层扫描(CT)显示Morgagni疝,胃和横结肠突出进入右胸腔。最初,由于她的年龄,对胃疝进行了内窥镜修复,这是成功的。然而,两天后她复发了,促使我们进行半紧急腹腔镜手术。腹腔镜检查显示有Morgagni缺陷,用网膜,横结肠,胃突出,胃因气腹而缩小。幸运的是,突出的器官可以很容易地重新定位到腹部,没有粘连。疝缺损测量为6x3厘米。我们用腹外缝合进行了初次闭合。未进行囊切除。手术持续98分钟。术后第1天开始口服,患者于术后第3天出院,无并发症。术后1个月胸部X线和CT扫描显示无复发,在9个月的随访检查中,患者仍无症状。根据我们的审查结果,原发性闭合是治疗小疝缺损的有效方法(经验法则:宽度,<4厘米;长度,<7厘米)。
    We report a case of a Morgagni hernia repaired by primary closure with an extra-abdominal suture. Moreover, we reviewed cases of laparoscopically repaired Morgagni hernia, in which the size of the hernia defect was known, to establish a size criterion for mesh utilization. An 87-year-old woman presented to our hospital with right upper abdominal pain and vomiting. She had no history of abdominal surgery or trauma. Chest radiography and computed tomography (CT) revealed a Morgagni hernia, with the stomach and transverse colon herniated into the right chest cavity. Initially, an endoscopic repair was performed for the herniated stomach due to her age, which was successful. However, she had a recurrence 2 days later, prompting us to perform a semi-emergent laparoscopic surgery. Laparoscopic examination revealed a Morgagni defect, with the omentum, transverse colon, and stomach herniated, with the stomach reduced by pneumoperitoneum. Fortunately, the herniated organs could be easily relocated into the abdomen with no adhesions. The hernia defect measured 6 x 3 cm. We performed primary closure with an extra-abdominal suture. No sac resection was performed. The operation lasted 98 min. Oral intake was initiated on postoperative day 1, and the patient was discharged on postoperative day 3 without complications. Chest radiography and CT scans at 1 month postoperatively showed no recurrence, and the patient remained asymptomatic at the 9-month follow-up examination. According to our review findings, primary closure is an efficient method for small hernia defects (rule of thumb: width, <4 cm; length, <7 cm).
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  • 文章类型: Journal Article
    通过量化来自治疗前CT图像的瘤内异质性,研究接受新辅助免疫化疗(NAIC)的非小细胞肺癌(NSCLC)患者的病理完全缓解(pCR)的预测。
    这项回顾性研究包括在4个不同中心接受NAIC的178例NSCLC患者。训练组包括来自A中心的108名患者,而外部验证集由来自中心B的70名患者组成,中心C,和中心D.传统的影像组学模型使用影像组学特征进行了对比。提取感兴趣的肿瘤区域(ROI)内的每个像素的影像组学特征。使用K均值无监督聚类方法确定肿瘤子区域的最佳划分。使用来自每个肿瘤子区域的生境特征开发了内部肿瘤异质性生境模型。本研究采用LR算法构建机器学习预测模型。使用诸如受试者工作特征曲线下面积(AUC)等标准评估模型的诊断性能,准确度,特异性,灵敏度,阳性预测值(PPV),和阴性预测值(NPV)。
    在培训队列中,传统的影像组学模型的AUC为0.778[95%置信区间(CI):0.688-0.868],而肿瘤内部异质性生境模型的AUC为0.861(95%CI:0.789-0.932)。肿瘤内部异质性生境模型表现出更高的AUC值。它显示了0.815的准确性,超过了传统的影像组学模型所达到的0.685的准确性。在外部验证队列中,两个模型的AUC值分别为0.723(CI:0.591-0.855)和0.781(95%CI:0.673-0.889),分别。生境模型继续表现出更高的AUC值。在准确性评估方面,肿瘤异质性生境模型优于传统的影像组学模型,与0.686相比,得分为0.743。
    使用CT对接受NAIC的NSCLC患者的肿瘤内异质性进行定量分析以预测pCR,有可能为可切除的NSCLC患者的临床决策提供信息。防止过度治疗,并实现个性化和精确的癌症管理。
    UNASSIGNED: To investigate the prediction of pathologic complete response (pCR) in patients with non-small cell lung cancer (NSCLC) undergoing neoadjuvant immunochemotherapy (NAIC) using quantification of intratumoral heterogeneity from pre-treatment CT image.
    UNASSIGNED: This retrospective study included 178 patients with NSCLC who underwent NAIC at 4 different centers. The training set comprised 108 patients from center A, while the external validation set consisted of 70 patients from center B, center C, and center D. The traditional radiomics model was contrasted using radiomics features. The radiomics features of each pixel within the tumor region of interest (ROI) were extracted. The optimal division of tumor subregions was determined using the K-means unsupervised clustering method. The internal tumor heterogeneity habitat model was developed using the habitats features from each tumor sub-region. The LR algorithm was employed in this study to construct a machine learning prediction model. The diagnostic performance of the model was evaluated using criteria such as area under the receiver operating characteristic curve (AUC), accuracy, specificity, sensitivity, positive predictive value (PPV), and negative predictive value (NPV).
    UNASSIGNED: In the training cohort, the traditional radiomics model achieved an AUC of 0.778 [95% confidence interval (CI): 0.688-0.868], while the tumor internal heterogeneity habitat model achieved an AUC of 0.861 (95% CI: 0.789-0.932). The tumor internal heterogeneity habitat model exhibits a higher AUC value. It demonstrates an accuracy of 0.815, surpassing the accuracy of 0.685 achieved by traditional radiomics models. In the external validation cohort, the AUC values of the two models were 0.723 (CI: 0.591-0.855) and 0.781 (95% CI: 0.673-0.889), respectively. The habitat model continues to exhibit higher AUC values. In terms of accuracy evaluation, the tumor heterogeneity habitat model outperforms the traditional radiomics model, achieving a score of 0.743 compared to 0.686.
    UNASSIGNED: The quantitative analysis of intratumoral heterogeneity using CT to predict pCR in NSCLC patients undergoing NAIC holds the potential to inform clinical decision-making for resectable NSCLC patients, prevent overtreatment, and enable personalized and precise cancer management.
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  • 文章类型: English Abstract
    Automatic detection of pulmonary nodule based on computer tomography (CT) images can significantly improve the diagnosis and treatment of lung cancer. However, there is a lack of effective interactive tools to record the marked results of radiologists in real time and feed them back to the algorithm model for iterative optimization. This paper designed and developed an online interactive review system supporting the assisted diagnosis of lung nodules in CT images. Lung nodules were detected by the preset model and presented to doctors, who marked or corrected the lung nodules detected by the system with their professional knowledge, and then iteratively optimized the AI model with active learning strategy according to the marked results of radiologists to continuously improve the accuracy of the model. The subset 5-9 dataset of the lung nodule analysis 2016(LUNA16) was used for iteration experiments. The precision, F1-score and MioU indexes were steadily improved with the increase of the number of iterations, and the precision increased from 0.213 9 to 0.565 6. The results in this paper show that the system not only uses deep segmentation model to assist radiologists, but also optimizes the model by using radiologists\' feedback information to the maximum extent, iteratively improving the accuracy of the model and better assisting radiologists.
    基于电子计算机断层扫描(CT)影像的肺结节自动检测可以有效辅助肺癌诊治,但当前缺乏有效的交互工具将放射科医生的判读结果实时记录并反馈,以优化后台算法模型。本文设计并研发了一个支持CT图像肺结节辅助诊断的在线交互审查系统,通过预置模型检测出肺结节展示给医生,医生利用专业知识对检测的肺结节进行标注,然后根据标注结果采用主动学习策略对内置模型进行迭代优化,以持续提高模型的准确性。本文以开源肺结节数据集——肺结节分析2016(LUNA16)的5~9号子集进行迭代实验,随着迭代次数的增加,模型的准确率、调和分数和交并比指标稳定提升,准确率从0.213 9提高至0.565 6。本文研究结果表明,该系统能在使用深度分割模型辅助医生诊断的同时,最大程度地利用医生的反馈信息来优化模型,迭代提高模型的准确性,从而更好地辅助医生工作。.
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  • 文章类型: Journal Article
    COVID-19大流行的发作使医生在疾病的急性期获得了肺部超声(LUS)的经验。然而,在恢复阶段,LUS发现的数据有限。这项研究的目的是评估LUS评估COVID-19后综合征患者肺部受累的实用性。这项研究前瞻性招募了72例接受配对LUS和胸部CT扫描(112对包括随访)的患者。最常见的CT表现为磨玻璃影(83.3%),胸膜下线(72.2%),牵引支气管扩张(37.5%),和合并(31.9%)。LUS最初显示不规则的胸膜线是常见的异常(56.9%),伴随胸膜下实变>2.5mm≤10mm(26.5%)和B线(26.5%)。LUS评分之间有很强的相关性,CT中描述的毛玻璃混浊的人工智能百分比计算(r=0.702,p<0.05)。与无纤维化组相比,具有纤维化改变的组的LUS评分显著更高,平均值分别为19.4±5.7至11±6.6(p<0.0001)。LUS可能被认为对从COVID-19肺炎恢复后持续症状的患者进行检查是有价值的。通过LUS识别的异常与CT扫描结果一致;因此,LUS可能会减少频繁的胸部CT检查的需要。
    The onset of the COVID-19 pandemic allowed physicians to gain experience in lung ultrasound (LUS) during the acute phase of the disease. However, limited data are available on LUS findings during the recovery phase. The aim of this study was to evaluate the utility of LUS to assess lung involvement in patients with post-COVID-19 syndrome. This study prospectively enrolled 72 patients who underwent paired LUS and chest CT scans (112 pairs including follow-up). The most frequent CT findings were ground glass opacities (83.3%), subpleural lines (72.2%), traction bronchiectasis (37.5%), and consolidations (31.9%). LUS revealed irregular pleural lines as a common abnormality initially (56.9%), along with subpleural consolidation >2.5 mm ≤10 mm (26.5%) and B-lines (26.5%). A strong correlation was found between LUS score, calculated by artificial intelligence percentage involvement in ground glass opacities described in CT (r = 0.702, p < 0.05). LUS score was significantly higher in the group with fibrotic changes compared to the non-fibrotic group with a mean value of 19.4 ± 5.7 to 11 ± 6.6, respectively (p < 0.0001). LUS might be considered valuable for examining patients with persistent symptoms after recovering from COVID-19 pneumonia. Abnormalities identified through LUS align with CT scan findings; thus, LUS might potentially reduce the need for frequent chest CT examinations.
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